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What’s Pre-implantation Genetic Testing?
Pre-implantation genetic testing (PGT) is a crucial step in IVF, where embryos are checked for genetic or chromosomal issues. This process helps identify the healthiest embryo, ultimately lowering the risk of miscarriage or the chance of having a baby with genetic conditions. If you’re considering IVF, this could be a significant option for you.
Types of PGT
- PGT-A: This test looks for issues with chromosome numbers, known as aneuploidy. Embryos with these abnormalities are more likely to lead to miscarriages or genetic disorders like Down syndrome.
- PGT-M: This test targets specific genetic disorders caused by mutations in a single gene, such as cystic fibrosis and Huntington’s disease. At TFP Oxford Fertility, you may even find NHS funding available for PGT-M!
- PGT-SR: This examines structural changes in chromosomes that might result in developmental issues or repeated miscarriages. These alterations can be inherited or occur spontaneously.
How PGT Works
If you decide to go through with PGT during your IVF journey, we’ll carefully extract a small sample of cells from each embryo after allowing them to develop for about 5-6 days. Those samples are sent to the Cooper Genomics Laboratory in London, where skilled embryologists perform the testing.
Once the biopsy is done, your embryos are frozen until we have the results. The DNA from these cells is then analyzed to check for chromosomal counts or specific genetic conditions. This process usually takes about four weeks. Once we have the results, we can choose the healthiest embryos for transfer during your IVF cycle.
Cost of PGT
The cost varies based on the type of testing and how many embryos you want to examine. PGT is an added expense to your IVF treatment. For instance:
- PGT-A: £870 (includes biopsy and testing)
- PGT-M: £2,870 (includes biopsy and freezing)
- PGT-SR: £1,810 (includes biopsy and freezing)
- Additional embryos: £500 each
If you’re curious about pre-implantation genetic testing or want to chat about funding options, don’t hesitate to reach out to our supportive team.
Real Stories
- Jamie’s Journey: Jamie always envisioned being a solo parent. After facing the risk of passing on a genetic condition, IVF with PGT gave Jamie hope for a healthy family.
- Liam and Sara’s Success: After multiple losses and a family history of Down syndrome, PGT helped Liam and Sara finally welcome their beautiful daughter.
- Anna’s Breakthrough: After discovering she had a significant risk of muscular dystrophy, Anna sought PGT, ensuring her child would be free from the condition.
- Ethan and Mia’s Lockdown Experience: Despite the challenges of lockdown, they pursued IVF with PGT to prevent passing down polycystic kidney disease.
Fertility Support
As part of your treatment, you’ll have access to specialized fertility counseling. This can be a game changer as you navigate your options and expectations. We’re here to support you every step of the way.
If you’re ready to embark on your fertility journey or have questions, reach out to our team for guidance and to schedule your first consultation with a fertility expert.
Summary
Pre-implantation genetic testing (PGT) is an essential step in IVF that checks embryos for genetic and chromosomal abnormalities, helping to ensure healthier outcomes and reduce the risk of miscarriage. There are different types of PGT tailored to specific needs, and the testing process involves careful cell sampling and DNA analysis. Costs can vary based on the type of PGT chosen. We also emphasize the importance of support throughout your journey, including access to counseling. For those looking for further information, resources like RESOLVE can be incredibly helpful for understanding family-building options.