PFC Staff Showcase Research at ESHRE Annual Meeting

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Hey friends! We’re excited to share that our team recently presented two fascinating scientific posters at the Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) in beautiful Lisbon, Portugal from June 14–17, 2015.

Exploring AMH Levels and IVF Outcomes

The first poster, co-authored by Dr. Laura Stone and research assistant Jamie Brooks, explored the question: “Can Anti-Müllerian Hormone (AMH) Levels Predict IVF Outcomes with Pre-Implantation Genetic Screening (PGS)?” AMH is a key protein produced by reproductive tissue that gives insight into the egg supply. Analyzing 288 IVF/PGS cycles from June 2010 to July 2013, they found a solid link between higher AMH levels and the number of chromosomally normal embryos produced. Essentially, women with elevated AMH levels had better chances of achieving a live birth after egg retrieval, along with lower pregnancy loss rates. Dr. Stone noted, “While this study confirmed that low AMH is associated with poorer outcomes, it also highlighted that identifying a chromosomally normal embryo can significantly improve chances of success.” In fact, even with AMH levels under 1.0 ng/mL, the live birth rate for transfers of euploid embryos was 53 percent.

IVF Outcomes for Patients Undergoing PGS

The second poster, co-authored by Jamie Brooks, Dr. Laura Stone, and Dr. Mark Taylor, was titled “IVF Outcomes for Patients Undergoing PGS.” This research looked at the probability of producing euploid embryos based on age, analyzing 433 IVF/PGS cycles. The findings confirmed that the likelihood of producing euploid embryos decreases as age increases. Dr. Stone explained, “We’ve always advised patients about age-related outcomes, but this research provides concrete data to help them set realistic expectations.” For instance, a 35-year-old woman might expect one normal embryo for every six eggs retrieved, while women aged 43 to 45 may need to produce up to 42 eggs to find a normal embryo. Nevertheless, cycles that yielded at least one euploid embryo for a frozen transfer had a remarkable live birth rate of 72 percent!

Further Resources

If you’re interested in understanding more about fertility treatments, you can check out this insightful post on why someone chose home insemination and found success in their journey to parenthood. For those considering artificial insemination, resources like this one can also be really helpful. Don’t forget to check out the BabyMaker at Home Insemination Kit for a reliable option too.

Conclusion

In summary, our team’s presentations at ESHRE contributed valuable insights into the correlations between AMH levels, age, and live birth rates, empowering patients with better knowledge to navigate their fertility journeys.