Genetic Testing Boosts Success Rates for Fertility Treatments

man with ear on pregnant bellyGet Pregnant Fast

Hey friends! Today, let’s talk about how genetic testing is making a big difference in fertility success rates. With all the advancements in technology, including improved freezing methods and biopsy techniques, we’ve seen some remarkable changes in the way fertility treatments work.

According to Dr. Emily Stone, a certified genetic counselor, genetic testing has come a long way. “We’ve been offering chromosome screening for over a decade,” she shares. “But we really embraced comprehensive chromosome screening (CCS) because it’s way more accurate than older methods. Now, we provide CCS to most of our patients.”

What is Comprehensive Chromosome Screening (CCS)?

So, what exactly does CCS do? It uses a DNA method called microarray to check for any imbalances in chromosomal material. Dr. Stone explains, “It tests all 23 pairs of chromosomes, identifying any extra or missing chromosomes.” This is super important because abnormal chromosome numbers are pretty common in early embryos. CCS helps pinpoint embryos with the right number of chromosomes, known as euploid embryos.

Understanding the Limitations of CCS

However, Dr. Stone emphasizes that patients often confuse what CCS can and can’t do. “CCS specifically tests for chromosomal abnormalities, like Down syndrome, which can occur randomly and is more frequent in older women,” she notes. But it doesn’t screen for birth defects that aren’t linked to chromosomal issues, such as heart defects or autism, nor does it check for certain genetic diseases like cystic fibrosis or Huntington’s disease. For those, a different approach called preimplantation genetic diagnosis (PGD) can be used, though it’s not as common as CCS.

The Results of Using CCS

The results? Using CCS to select embryos with normal chromosomes has led to lower miscarriage rates and significantly improved implantation and ongoing pregnancy rates. “It’s a game changer for determining which embryos might lead to successful pregnancies,” Dr. Stone adds. In fact, by transferring a single euploid embryo after IVF, success rates have skyrocketed to about 50–75% per transfer across all age groups! This method also keeps multiple gestation rates below 2%, reducing the risk of miscarriage and conditions like Down syndrome.

For younger women, CCS enhances pregnancy rates and helps preserve viable embryos for future use. For older women, who often have fewer euploid embryos, the benefits are even more pronounced. Dr. Stone notes, “Women aged 35 to 42 are at a higher risk for chromosomal abnormalities, but they can still generate enough embryos to find healthy ones for transfer.”

Of course, some patients, especially older ones, might need to go through multiple cycles to find a normal embryo. At our clinic, we prioritize transferring only euploid embryos. Dr. Stone reassures patients that genetic testing is completely optional: “We make sure to educate patients about this before proceeding with CCS.”

Additional Resources

If you’re curious about the process of transferring frozen embryos, check out this informative post on frozen embryo transfers—there’s a lot to learn! For those interested in home insemination options, the BabyMaker kit is a great authority on the topic. And if you want more insights into family-building options, don’t forget to explore this excellent resource.

Conclusion

In summary, genetic testing, specifically CCS, is revolutionizing fertility treatment success rates by identifying healthy embryos for transfer, ultimately leading to higher chances of pregnancy and lower risks of complications.