Fresh vs. Frozen Embryo Transfer Success Rates

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When it comes to embryo transfers in the IVF process, there’s a lot of chatter about the success rates of fresh versus frozen embryos. Researchers and fertility specialists often point out that frozen embryo transfers tend to yield better pregnancy outcomes compared to fresh ones. However, success rates are just one piece of the puzzle. Depending on individual circumstances, one option may be more beneficial than the other. Let’s dive into what you should consider when deciding between fresh and frozen embryo transfers.

What’s the Difference?

Both fresh and frozen embryo transfers start with ovulation induction and monitoring. Once the uterus is prepared, egg retrieval takes place. After collecting the eggs, they’re fertilized using sperm from a partner or donor. In the case of a fresh embryo transfer, the fertilized embryo is placed back into the uterus about three to five days later. Alternatively, during a frozen embryo transfer (FET), embryos can be kept on ice and used later—sometimes even years down the line.

Comparing Success Rates

Recent studies have indicated that frozen embryos often lead to higher success rates than fresh ones. For instance, a 2018 study from the New England Journal of Medicine showed women with polycystic ovary syndrome (PCOS) had better live birth rates with frozen embryos. Conversely, research from the British Medical Journal found no significant differences in ongoing pregnancies among women using FET if they had regular cycles.

Moreover, research from 2019 found that the quality of embryos plays a key role: higher-quality embryos boast a live birth rate of 79%, while poorer-quality ones only achieve a 28% live birth rate. Your age and health during the transfer, as well as the sperm quality, significantly influence these outcomes.

Benefits of Frozen Embryo Transfers

While success rates are important, there are other factors to consider when choosing between fresh and frozen transfers:

  1. Cost-Effectiveness: IVF can be pricey, and having frozen embryos can save you from repeating the costly cycle of medication and retrieval if your first attempt doesn’t go as planned.
  2. Flexibility in Timing: Life can be unpredictable. With frozen embryos, you can plan when to transfer them, allowing for a more controlled approach to starting a family.
  3. Reduced Physical and Mental Stress: Fresh transfers can be taxing on the body due to the need for egg stimulation and retrieval. FETs usually require less medication and stress since the embryos are already prepared.
  4. Natural Cycle Mimicking: Since fresh transfers happen shortly after egg retrieval, hormone levels may still be elevated, which could hinder implantation. FETs can be timed better to create a more favorable environment for the embryo.
  5. Genetic Testing and Selection: Freezing allows for testing embryos for genetic disorders or to select embryos based on sex, increasing the chances of a successful pregnancy.

If you’re curious to learn more about personal experiences with fertility, you might want to check out this blog post on Lena’s journey with vaginismus here. Also, for those interested in artificial insemination, resources from Make a Mom can be quite informative. Additionally, if you’re seeking knowledge about pregnancy, Healthline provides excellent resources.

Summary

In summary, while frozen embryo transfers may offer higher success rates and various benefits, the choice between fresh and frozen should be tailored to individual circumstances. Consulting a trusted fertility center can help you determine the best route for your unique situation.