Artificial Insemination: ICI and IUI Side Effects

Diagram of egg cell and sperm cell with a text about artificial insemination

Starting a journey with artificial insemination can feel overwhelming, especially when considering potential side effects. Regardless of if you are exploring ICI or IUI at home, it’s important to understand what potential side effects might arise.

While most side effects are mild and temporary, knowing what to expect helps you feel more prepared and confident on your path to conception. 

What Is Artificial Insemination?

Explanation of artificial insemination as a fertility treatment, with a model of the female uterus

Artificial insemination is a fertility treatment that delivers sperm directly to the cervix or uterus, aiming to increase the chances of pregnancy. This can be done through two main procedures: Intrauterine Insemination (IUI) or Intracervical Insemination (ICI), both designed to enhance fertility outcomes by bypassing some barriers to conception.

How Does Artificial Insemination Work, and When Should It Be Timed?

Doctors plan artificial insemination (AI) around your menstrual cycle to increase the chances of success. The best time for AI is when ovulation occurs—about 14 days before your period—because this is when the ovary releases a mature egg. 

To confirm ovulation, doctors use blood and urine tests, along with at-home kits. AI is usually done once per cycle. There are two main methods of artificial insemination: IUI and ICI, both of which aim to help fertilization.

What is Intrauterine Insemination?

Explanation of intrauterine insemination (IUI) as a fertility treatment, with a uterus diagram.

Intrauterine insemination (IUI) is a fertility treatment often used for male infertility but can also help with unexplained infertility, endometriosis, or thick cervical mucus. The process involves fertility medications, followed by sperm preparation to separate it from seminal fluid, which could cause uterine contractions. 

A catheter is used to place the sperm directly into the uterus, reducing the distance to the egg and increasing the chances of conception. Success rates vary: 8-10% for male infertility, 5% for tubal issues, and 18-20% for unexplained infertility.

What is Intracervical Insemination?

Overview of intracervical insemination (ICI) as a fertility treatment, showing a syringe near cervix

Intracervical Insemination (ICI) is a straightforward fertility treatment that mimics natural intercourse. It involves placing liquefied, unwashed semen (from a donor or partner) into a syringe, which is then inserted into the vagina near the cervix. 

The person trying to conceive should lie down for about 30 minutes to help the sperm reach the fallopian tubes. ICI pregnancy can be done at home or in a medical center, with success rates ranging from 5% to 30%. Using a sponge cap or sperm washing can increase effectiveness. 

ICI and IUI Side Effects 

List of ICI and IUI side effects

Artificial insemination techniques, such as Intrauterine Insemination (IUI) and Intracervical Insemination (ICI), offer fertility solutions but come with potential side effects. For IUI, common side effects include mild cramping, light bleeding or spotting, bloating, nausea, and emotional fluctuations due to fertility medications.

ICI, a simpler method, may cause slight cramping, discomfort, or light bleeding, especially if sperm is washed beforehand. While the risks are generally low, there are still minimal chances of infection or injury if the procedure isn’t done correctly. It’s important to consult a healthcare provider to discuss these potential risks.

ICI and IUI Risks

List of ICI and IUI Risks

While IUI and ICI are generally low-risk procedures, some complications can arise. These include a slight risk of pelvic infection, ovarian hyperstimulation syndrome (OHSS) due to fertility medications, and an increased chance of multiple pregnancies when fertility drugs are used alongside insemination. 

While insemination itself doesn’t directly cause multiple pregnancies, combining it with medication can raise the likelihood of twins or more. It’s important to be aware of these risks and discuss them with your healthcare provider.

What is the Cost of Artificial Insemination?

Overview of the cost of artificial insemination

If you’re wondering, “How much is an IUI?” The cost generally ranges from $300 to $1,000 per cycle without insurance, with additional charges for donor sperm ($700–$1,000 per vial). ICI is generally more affordable, costing between $200 and $350 per cycle, with sperm washing or donor sperm increasing the price. 

Since IUI and ICI often require multiple cycles for success, some may consider IVF, which costs around $15,000 but offers a higher success rate (about 53.9% for those under 35). Insurance may cover some of these expenses, including tests and medications.

Maximizing Success in IUI & ICI

If you’re considering artificial insemination, it’s essential to understand potential side effects and risks of IUI and ICI to make informed decisions. Side effects like cramping or light bleeding are common but generally mild. Working closely with a fertility specialist, tracking your cycle carefully, and preparing for both the financial and emotional aspects can help you maximize your chances of success.

At Intracervical Insemination, we’re here to guide you every step of the way.  Don’t wait—take action now by consulting a healthcare provider to discuss your options and plan your path to conception. Every step brings you closer to your goal.

FAQs

Can you use ICI vials for IUI?

ICI vials can be used for any type of insemination, similar to IUI vials. However, for use in IUI or IVF procedures, a healthcare professional must first wash the samples to prepare them properly.

How long to lie down after ICI?

After the procedure, the woman should rest for 15 to 30 minutes to give the sperm enough time to travel to the uterus. According to the American Pregnancy Association, ICI has a higher success rate compared to timed intercourse, making it a more effective option for achieving pregnancy.

Is IUI 100% successful?

No, IUI, like other fertility treatments, cannot guarantee a 100% success rate. The chances of success depend on several factors, including individual health, fertility issues, and the combination of IUI with fertility medications. On average, the artificial insemination success rate for IUI treatment cycles is around 15% to 20%.

How can I improve my ICI success?

To maximize your chances of success, it’s important to time insemination with your ovulation cycle. We recommend tracking your ovulation for a couple of months before the procedure to ensure it’s performed during your peak fertility days.  This will help increase the likelihood of successful conception and improve your ICI success rate.