At the UCSF Center for Reproductive Health, we offer two main types of genetic tests for embryos prior to implantation: preimplantation genetic testing for aneuploidy (PGT-A) (previously called PGS) and preimplantation testing for monogenic disorders (PGT-M) (formerly known as PGD).
What is PGT-A?
PGT-A serves as a screening tool that assesses the embryo’s chromosomes, which are the carriers of our genetic information. Ideally, an embryo should have 46 chromosomes—half from the egg and half from the sperm. PGT-A looks for any missing or extra chromosomal material, within the limits of the test’s resolution. Chromosomal abnormalities can lead to unsuccessful implantation, miscarriage, or affect the future health of the child. While PGT-A does not alter the chromosomes in any way, an embryo that passes this screening has a lower risk of these issues compared to one that has not been screened.
Did You Know?
The age of the egg provider is the primary factor influencing the risk of chromosomal abnormalities in embryos. If you’re curious about how egg freezing works, check out this post for more details. It’s also worth noting that for those considering at-home options, you might want to explore resources on artificial insemination, which can offer valuable insight into the process.
Conclusion
In summary, preimplantation genetic testing can provide essential information about embryos, potentially increasing the chances of a successful pregnancy by ensuring that the embryos are chromosomally normal.
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